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The authors attributed the effect mainly to ERR engagement in cardiomyocytes, which normalized fatty acid metabolism and mitochondrial function without reversing hypertrophy itself

Research documents inflammation markers in TB-500-treated versus control tissues

Intestinal macrophages and response to microbial encroachment

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The entry of copper ion carriers into the cell leads to copper accumulation, which in-turn, triggers oxidative stress and induces cell death (Fig